The event, founded by activism collective Surge in 2016, is expected to bring together around 10,000 people in London alone, compared to 2017's 5000 - numbers have doubled every year.
London is one of 23 marches taking place across the world on August 25, with 20,000 expected to march globally.
The aim of the march, which will take vegan demonstrators from Westminster to Hyde Park, is to end all animal oppression.
In addition, it will celebrate the successes achieved within the vegan animal rights movement, but also show solidarity for all those who are still being needlessly exploited all around the world.
According to Surge: "By marching through central London, the event also raises awareness of the plight of nonhuman animals to the thousands of bystanders and shows the exponential growth of veganism within the UK and indeed across the world."
'Society must wake up'
Ed Winters, Co-Founder and Co-Director of Surge, said: "For too long, non-human persons have been seen unworthy of consideration within society, treated as objects and property.
"This march is an embodiment of society's changing attitudes towards non-human animals and is a precursor for a world that doesn't just talk about equality and peace but also lives by it.
"The lives of non-human animals belong only to them and their existence on this planet is as valuable to them as ours is to us. Society must wake up and no longer treat life that does not resemble our own as inferior or less worthy. The future is vegan, so the only question is, which side of history do you choose to stand on?"
The march will start at Millbank, SW1P 3JA, and end in Hyde Park where speeches will commence.
Ed Winters and high-profile vegan campaigner and actor Evanna Lynch will be among the speakers to take to the stage.
The Official Animal Rights March is a global event, with events taking place in 23 other cities across the world including Berlin, Manila, Melbourne and New York.