The dairy-free pizza, which costs £12.50, is topped with four types of vegan cheese - Mozzarisella - original, smoked, cheddar and blue.
"Over the past year we've seen vegan dishes become more popular than ever and we're anticipating that this January will be the biggest Veganuary yet," Kathryn Turner, Director of Food Development at Zizzi, said in a statement sent to Plant Based News.
"Our vegan customers tell us it's important that they have a wide choice and are not just 'stuck' with one option from the menu.
"We hope they'll love our first four vegan cheese pizza and hope it will help first-time vegans get their cheese fix this month. We can't wait to hear what our customers think."
"Veganuary is creating a new wave of consumers and shoppers with both strong ethics and a big appetite," Simon Winch, Veganuary CEO, added. "Right now, there is a real opportunity for brands, retailers and restaurants to improve, expand and promote their vegan and plant-based offerings to a wider audience.
"We're delighted that Zizzi is one of those companies that's risen to this challenge - helping us to create the change we desire and provide the product to meet the consumer demand – we can't wait to try the Quattro No-Maggio!"
The Quattro No-Maggio is available nationwide from January 8 and in selected restaurants from January 2. It is part of Zizzi's special two-for-one offer on all vegan mains throughout the month.