The Vegan Festive Pizza features a red wine gravy base with Sheese cheese, Brussel sprouts, carrots and parsnips, topped with a cranberry drizzle.
The pizza giant has partnered Crisis this Christmas and will donate 50p from every purchase of the Festive Meal Deal to the charity.
"We're really proud to be working with Crisis this Christmas, a charity that aims to eradicate homelessness and provides vital services to people in the UK at one of the hardest times of the year," Papa John's Marketing Director, Giles Codd, said.
"Our 'Christmas is Better Shared' campaign highlights the fact that this should be a time for being with people and looking after each other, and what better way to do it than over a pizza with friends and loved ones.
'With several ways to donate to charity including the newly created festive merchandise store, we are hoping to smash our fundraising targets in order to help Crisis continue the fantastic work they do not just at Christmas, but throughout the whole year."
Jon Sparkes, chief executive of Crisis, added, "Our society is stronger when we work together, and by working with partners, such as Papa John's, we are able to raise awareness of homelessness and vital funds so that we can deliver our services ranging from education to housing and employment support."